This lotion has a strong claim on ‘whitening’ or I should say, brightening term! The study was not done with real people on real skin but still - using a good sunscreen next to MP containing products is a good idea. Us… It seems to us that squalane is in fashion and there is a reason for it. See the list … It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. BTW, it’s also a food additive. View entire discussion ( 52 comments) More posts from the AsianBeauty community. A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). A natural moisturizing factor that compared to glycerin penetrates slower into the skin but gives longer lasting moisture and less sticky, better skin-feel. If HA does not tell you anything we have a super detailed, geeky explanation about it here. A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. The TL; It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It’s a light gel, hardly runny at all. There are quite a few Hada Labo lotions available, all suited to different skin types and concerns as outlined below. It is a good emulsifier choice for stable water-resistant sunscreen formulas. Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. A real oldie but a goodie. An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. Not penetrating the skin but mostly just sitting on top of it and not containing biologically active components, like nice fatty acids and vitamins mean that mineral oil does not "nourish" the skin in the way plant oils do. In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy. The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). Good old water, aka H2O. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert. Hada Labo Gokujyun Premium Emulsion. Works in synergy with Vitamin C. Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The Gokujyun Premium Emulsion is a milky fluid that goes on the skin like water. Hada Labo Gokujun Premium Hyaluronic Emulsion Cream Fall 2020 Renewal 140mL $15.29 ($15.29 / Count) In Stock. One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). It's not only soothing but it' also skin-softening and protecting and can promote wound healing. A 2005 study titled "Is mineral oil comedogenic?" It can bind huge amounts of water and it's pretty much the current IT-moisturizer. Also used for scar treatment. (You can read much more about HMW and LMW HA here in the geeky details section.). Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. Benefits: Contains 5 kinds of hyaluronic acid (moisturizing ingredient) as much as a serum. A fatty acid that can be found naturally in the skin. the condition rank : New. It also occurs naturally in our body and is used as a food additive. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne. It is typically used in tiny amounts, around 0.1% or even less. It has a pleasant non-sticky, non-greasy feel to it, gives formulas smooth application properties and also helps moisture retention. It leaves a nice non-greasy, non-heavy feeling on the skin. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. Hydrolyzed Hyaluronic Acid (Nano Hyaluronic Acid), Read all the geeky details about Tocopherol here >>, click here and read about all the details, Read all the geeky details about Glycerin here >>, Primary fat-soluble antioxidant in our skin, Significant photoprotection against UVB rays, Vit C + Vit E work in synergy and provide great photoprotection, Easy to formulate, stable and relatively inexpensive, A natural moisturizer that’s also in our skin, A super common, safe, effective and cheap molecule used for more than 50 years, Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier, Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot), High-glycerin moisturizers are awesome for treating severely dry skin. An error has occurred. lol. We do a Best of INCIDecoder email once a month with the most interesting products and ingredients we bump into. It is a great emollient and moisturizer working mainly by occlusivity. Rinse thoroughly. As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. It’s pretty much the current IT-preservative. This is no coincidence. It penetrates into the inside of the skin and prevents blemishes. Free from artificial fragrances, colorants, mineral oils … An amino acid-based emulsifier that helps water and oil to mix and stay that way. It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. Contains the largest amount of nano-sized hyaluronic acid in the history of Hada Labo ® Whitening Series. Where the classic Hada Labo Gokujyun Lotion is a runny liquid, the Hada Labo Gokujyun Premium Lotion is thick. However, if you do not like its origin or its heavy feeling or anything else about it, avoiding it has never been easier. If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature). Meadowfoam Oil - An emollient plant that is stable, non-greasy and rapidly absorbed. A colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth. MAP does solve the stability problem: it's stable up to pH 7, so far so good. We do a Best of INCIDecoder email once a month with the most interesting products and ingredients we bump into. Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). Badmouthing mineral oil is a favorite sport of many, it is a cheap material and being connected to petrolatum makes it fairly easy to demonize. Shirojyun skin care series includes three products: toner, emulsion and cream which all contain arbutin, the highly effective whitening ingredient that helps to decrease the melanin production to prevent freckle and dark spots. 801. Typically used at 1% or less in most formulations. Derma Lift Anti Aging Reviews - Ingredients In Hada Labo Anti Aging Main Idea Of Butler Is There Anti Aging Medicine Anti Aging Permanent Liquid Hair Color With Vitamin E Blue Black Anti Aging Skin Care Products For Women The History Of Whoo Jinyul Essence 1ml X 120pcs 120ml Anti Aging Newest Need skincare guides? Mineral oil does not give the skin any extra goodness, it is simply a non-irritating moisturizer working mainly by occlusivity. A super commonly used thickener and emulsion stabilizer. Great service. Hada Labo Gokujyun Premium Hyaluronic Acid Lotion contains 29 ingredients. What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. United States. It also forms a protective barrier on the skin and fills in fine lines. The big brother of glycerin. Compared to glycerin, it has a larger molecular structure (kind of a double glycerin). Concentrated hyaluronic acid helps skin lock in moisture. There are also scar treatment gels out there using dimethicone as their base ingredient. As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Pretty much the current IT-preservative. Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). Claimed to have five times the water-binding capacity of normal HA, also acts as an antioxidant and gives skin long-term moisture. It's not only soothing but it'. Apply a pea-size amount into palm and work into lather. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. We especially recommend it if you are after skin brightening as this seems to be the strongest point of MAP. An amino acid that is one of the primary building blocks of hair keratin and skin collagen. If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature). It also contains antioxidant components such as vitamin E as well as phytosterols. Hada Labo Shirojyun Premium Emulsion is free from SkinCarisma flagged Allergens Understanding the Identified Contact Allergens The EU's Scientific Committee on Consumer Safety (SCCS) has identified and established 26 cosmetic ingredients that are likely contact allergens (potential to cause skin allergies) as demonstrated in clinical or epidemiological studies. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". Posted by 4 days ago. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It's a natural moisturizing factor and might also help to speed up wound healing. It's readily biodegradable. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). A fatty acid that can be found naturally in the skin. It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol. A white to beige powder that helps oil and water to mix nicely together (aka oil in water emulsifier). Thanks. What is more, in terms of the general health effects of mineral oils used in cosmetics, a 2017 study reviewed the data on their skin penetration and concluded that "the cosmetic use of mineral oils and waxes does not present a risk to consumers due to a lack of systemic exposure. It has a pleasant non-sticky, non-greasy feel to it, gives formulas smooth application properties and also helps moisture retention. Once I am off some medications which make my skin super sensitive, I will add some acids and retinoids. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. This rich emulsion provides and retains skin moisture with hyaluronic acid in 5 different molecular sizes and urea. Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. Their formulas provide extreme hydration to even the driest of skin. Hada Labo Gokujyun Premium Hyaluronic Acid Lotion adalah produk hydrating toner yang mengandung 5 jenis hyaluronic acid yaitu Sodium Acetyl Hyaluronate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer dan Hydroxypropyltrimonium Hyaluronate. Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. The better affinity comes from the acetyl groups that act as tiny "anchors" to attach the HA molecule to the skin. Usually the main solvent in cosmetic products. The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>. Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. Good old water, aka H2O. Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) sho. Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. (Well, in fact using a sunscreen is always a good idea. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. The cons of mineral oil It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid. Check out our wiki! :)), Hada Labo Shirojyun Premium Whitening Emulsion. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups. Vote for your favorites in the Best of SkincareAddiction Awards! It is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid. The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. The big brother of glycerin. A handy white powder that magically converts a liquid into a nice gel formula. Super common soothing ingredient. An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). Normal (well kind of - it's purified and deionized) water. AU $25.27. all the hada labo premium products are so A+ (the oil jelly, the cream, the lotion) but did anyone else have the shirojyun (the one with alpha arbutin) not agree with their face? Usually the main solvent in cosmetic products. Thanks to this, it penetrates slower into the skin but gives longer lasting moisture and less sticky, better skin-feel. The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. Blended white tranexamic acid ( Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It occurs naturally in certain fish and plant oils (e.g. A form of skincare superstar, Vitamin C. If you do not know, what the big deal about Vitamin C is, click here and read all about it, we will wait here for you. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. The emollient plant oil coming from the seeds of the white flowering plant called meadowfoam. It can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. **AM** - Hada Labo … Bottom line: when it comes to vitamin C derivatives, MAP is definitely an option. This lotion is from its Shirojyun range and contains tranexamic acid. This rich emulsion provides and retains skin moisture with hyaluronic acid in 5 different molecular sizes and urea. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. A handy white powder that magically converts a liquid into a nice gel formula. Was: AU $26.60. Works as an excellent surface hydrator in skincare. A very common silicone that gives both skin and hair a silky smooth feel. AU $21.88 postage. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". Super common little helper ingredient that helps products to remain nice and stable for a longer time. Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. Hada Labo – Hada Labo Gokujyun Premium Emulsion 140ml. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. Please try again later! Normal (well kind of - it's purified and deionized) water. So let us see them: The pros of mineral oil A form of skincare superstar, Vitamin C - it has proven skin-brightening abilities (in-vivo) and it might be able to boost collagen production as well (in-vitro). Everything under 20 bucks for the most part. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs. As f.c. Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. HADA LABO Shirojyun Premium lotion: rated 5 out of 5 on MakeupAlley. No wonder, it is a very popular and common ingredient. Triethylhexanoin is a colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. The other thing that mineral oil is really good at is being non-irritating to the skin. olive), and in the sebum (the oily stuff our skin produces) of the human skin. Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). For dry and super-sensitive skin types it is a great option. HADA LABO Goku-Jyun Premium Hyaluronic Acid Milky Emulsion - 140ml This milky emulsion is as light-weight as a lotion yet has the rich, moisture-locking power of a cream. As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Details Hada Labo Shirojyun Premium Whitening Lotion Contains anti-inflammatory white tranexamic acid (whitening active ingredient) and nanoized hyaluronic acid, vitamin C derivative and vitamin E as moisturizing ingredients. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. Moisturizing lotion contains tranexamic acid to help lighten and prevent the formation of dark spots, alongside Vitamin C and E offer protection against free radicals. Tiếp nối bài review serum Hada Labo Premium, thì hôm nay mình sẽ Review về em sữa dưỡng trắng da Hada Labo Nhật Shirojyun Premium Whitening Emulsion nha. The most common skincare ingredient of all. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben. ★★★ Hada Labo Tokyo Anti Aging Hydrator Walgreens Tretinoin Skin Anti Aging Phone Number For Allumiere Anti Aging Cream And Nutella Anti Aging Prevention 30281 Best Drug Store Prodeucts For Anti Aging Skin Care. This is my current skincare routine. A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. A fatty alcohol (the non-drying type) that is used to increase the viscosity of the formula and stabilize emulsions. It’s approved by Ecocert and also used in the food industry (E415). It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). Hada Labo Gokujyun Premium Hyaluron Emulsion is free from SkinCarisma flagged Allergens Understanding the Identified Contact Allergens The EU's Scientific Committee on Consumer Safety (SCCS) has identified and established 26 cosmetic ingredients that are likely contact allergens (potential to cause skin allergies) as demonstrated in clinical or epidemiological studies. Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. Hada Labo is arguably the most popular skin care brand in Japan, and it’s no secret why. If the product is too runny, a little xanthan gum will make it more gel-like. Digunakan untuk memberi kelembapan yang tahan lama di kulit wajah. We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>. olive), and in the sebum (the oily stuff our skin produces) of the human skin. The famous or maybe rather infamous mineral oil. Triethylhexanoin is a colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. Sodium Acetylhyaluronate (Super Hyaluronic Acid), Hydrolyzed Hyaluronic Acid (Nanosized Hyaluronic Acid), (Hyaluronan Hydroxy Propyltrimonium Skin-Adsorbed) Hyaluronic Acid, Hyaluronic Acid Cross Polymer - Na (3D Hyaluronic Acid), Read all the geeky details about Glycerin here >>, click here and read about all the details, Read all the geeky details about Hyaluronic Acid here >>, A natural moisturizer that’s also in our skin, A super common, safe, effective and cheap molecule used for more than 50 years, Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier, Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot), High-glycerin moisturizers are awesome for treating severely dry skin, It’s naturally in our skin and behaves there like a sponge, It can bind up to 1000 times its own weight in water, It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only), High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin, Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin), Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study), Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule. We don't have description for this ingredient yet. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA. In fact, it's the most common saturated fatty acid found in animals and plants. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water. Probably the most common silicone of all. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water. The lotion penetrates deep down, moisturizing and blocking the production of melanin, preventing the formation of wrinkles and freckles. But we have found comedogenic components, parabens and polyethylene glycol (PEG). It can sometimes be difficult to understand the range, as some product packaging is very similar and product names are … Even though it is a highly controversial ingredient, the scientific consensus is that it is a safe, non-irritating and effective emollient and moisturizer working mainly by occlusivity. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. An emulsion this smooth and creamy is unlike anything you've ever tried. Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups. One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben. It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. !Voting ends Jan 5! It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. Super common little helper ingredient that helps products to remain nice and stable for a longer time. It has a pleasant non-sticky, non-greasy feel to it and gives formulas smooth application properties. With the combined anti-inflammatory power of White Tranexamic Acid and the moisturizing power of nanoized Hyaluronic Acid and Vitamin C/E, Hada Labo HakuJun Premium Medicinal Whitening Lotion not only heals. 1,172 sold ☀Hada labo Super Hyaluronic Acid Moisturizing Milky lotion Gokujyun Rohto 140ml. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version). We have better news about the other two things: in-vitro data shows that MAP can boost collagen synthesis similar to AA (though in the case of AA it's proven in-vivo) and even better, MAP is proven to work as a skin brightener in-vivo (on real people).